Thirteen portals

The biology of growing old, the interventions aimed at slowing or reversing it, and the argument over how much of the lifespan ceiling is real.

Reading, editing, and writing genomes — from base editors and prime editors to synthetic chromosomes and the line at heritable change.

Who gets access, who decides, and what happens to institutions built on the assumption that people age and die on schedule.

Growing, printing, and replacing the parts that wear out — organs, tissue, limbs, blood — and why vascularization is still the wall.

Machines wired into nervous systems: brain–computer interfaces, implants, prosthetics, and the bandwidth problem that limits all of them.

The cross-cutting ideas — singularity, posthuman, readiness, precaution — that every other article eventually leans on.

The researchers, philosophers, and subcultures who built these ideas — and the arguments they have with each other.

Deliberately exceeding typical human capacity — cognitive, physical, sensory — and the therapy line that keeps refusing to stay put.

Emulation, uploading, and identity — what it would take to run a person on different hardware, and whether the result would be them.

The labs, companies, foundations, and prizes putting capital behind the field — and what they have shipped so far.

Gametes, embryos, and gestation: artificial wombs, in vitro gametogenesis, embryo selection, and inheritance made editable.

Intervention at molecular scale: DNA origami devices, steered microrobots, and the long distance between design studies and machines.

Bodies off Earth: radiation, microgravity, torpor, and the choice between terraforming the world and re-engineering the traveller.