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categories: ["people", "society"]categories: ["people", "society"]tags: ["bioethics", "enhancement", "embryo selection", "moral enhancement", "philosophy"]tags: ["bioethics", "enhancement", "embryo selection", "moral enhancement", "philosophy"]summary: "Australian bioethicist who formulated procreative beneficence and, with Ingmar Persson, the argument for moral bioenhancement; the leading academic advocate of human enhancement."summary: "Australian bioethicist who formulated procreative beneficence and, with Ingmar Persson, the argument for moral bioenhancement; the leading academic advocate of human enhancement."updated: "2026-08-23"updated: "2026-10-29"------ ```infobox```infoboxlines 29–36 → 29–3615 unchanged lines not shown
select the children expected to have the best lives, that enhancement is continuous with medicineselect the children expected to have the best lives, that enhancement is continuous with medicinerather than opposed to it, and that humanity's moral capacities are now the binding constraint onrather than opposed to it, and that humanity's moral capacities are now the binding constraint onits technological ones. Trained as a physician and as a philosopher under Peter Singer, he has beenits technological ones. Trained as a physician and as a philosopher under Peter Singer, he has beenthe most systematic academic defender of [[human-enhancement]] since the early 2000s, and thethe most systematic academic defender of [[human-enhancement]] since the early 2000s, and the figurefigure whose arguments [[bioconservatism|bioconservative]] critics most often answer.whose arguments [[bioconservatism|bioconservative]] critics most often answer. ## Career## Career lines 38–119 → 38–1181 unchanged line not shown
working on rationality and end-of-life decision-making. He took the Uehiro Chair in Practical Ethicsworking on rationality and end-of-life decision-making. He took the Uehiro Chair in Practical Ethicsat Oxford in 2002 and founded and directed the Oxford Uehiro Centre for Practical Ethics, whichat Oxford in 2002 and founded and directed the Oxford Uehiro Centre for Practical Ethics, whichbecame the main European base for analytic work on enhancement, neuroethics and research ethics. Hebecame the main European base for analytic work on enhancement, neuroethics and research ethics. Heedited the *Journal of Medical Ethics* for close to two decades. In August 2022 he moved hisedited the *Journal of Medical Ethics* for close to two decades. In August 2022 he moved his primaryprimary post to the National University of Singapore, where he is the Chen Su Lan Centennialpost to the National University of Singapore, where he is the Chen Su Lan Centennial Professor inProfessor in Medical Ethics and directs its Centre for Biomedical Ethics, while retaining OxfordMedical Ethics and directs its Centre for Biomedical Ethics. He retains Oxford and Melbourneand Melbourne affiliations, including a biomedical ethics group at the Murdoch Children's Researchaffiliations, including a biomedical ethics group at the Murdoch Children's ResearchInstitute.[^nus2022]Institute.[^nus2022] His output is unusually broad for the field: embryo selection, doping, organ donation, conscientiousHis output is unusually broad for the field. It covers embryo selection, doping, organ donation,objection by clinicians, the ethics of research in emergencies, and the ethics of pandemicconscientious objection by clinicians, the ethics of research in emergencies, and the ethics ofresponse — with Dominic Wilkinson he edited *Pandemic Ethics: From COVID-19 to Disease X*pandemic response; on the last, he and Dominic Wilkinson edited *Pandemic Ethics: From COVID-19 to(2023).[^pw2023]Disease X* (2023).[^pw2023] ## Procreative beneficence## Procreative beneficence The 2001 paper that made his name states a principle: couples who select embryos or gametes shouldThe 2001 paper that made his name states a principle: couples who select embryos or gametes shouldselect the child, of the possible children they could have, expected to have the best life, or atselect the child, of the possible children they could have, expected to have the best life, or atleast as good a life as the others, on the basis of relevant available information.[^savulescu2001]least as good a life as the others, on the basis of relevant available information.[^savulescu2001]The principle is deliberately narrow. It applies only where selection is already occurring, it doesThe principle is deliberately narrow. It applies only where selection is already occurring and doesnot license coercion, and it concerns non-person-affecting choices — the child selected is anot license coercion. It also concerns non-person-affecting choices, because the child selected is adifferent individual from the one who would otherwise have existed, which is why thedifferent individual from the one who would otherwise have existed, which is why the[[procreative-beneficence|non-identity problem]] does so much work in the surrounding literature.[[procreative-beneficence|non-identity problem]] does so much work in the surrounding literature. Savulescu extends the principle beyond disease traits to any characteristic that improves expectedSavulescu extends the principle beyond disease traits to any characteristic that improves expectedwellbeing, which is where the disagreement begins. If a test predicts a small advantage in somewellbeing, and that is where the disagreement begins. If a test predicts a small advantage in sometrait, the principle appears to make selection on it obligatory rather than optional — a conclusiontrait, the principle appears to make selection on it obligatory rather than optional, a conclusioncritics find either objectionable or a reductio. The argument has become directly practical withcritics find either objectionable or a reductio. The argument has become directly practical with thethe arrival of [[polygenic-embryo-screening]], which produces exactly the sort of probabilisticarrival of [[polygenic-embryo-screening]], which produces exactly the sort of probabilistic traittrait information the principle takes as input; Savulescu has argued that the resulting obligationsinformation the principle takes as input. Savulescu has argued that the resulting obligations areare modest because the predicted gains are small, while objecting to bans on the technology as such.modest because the predicted gains are small, while objecting to bans on the technology as such. > [!debate] The strongest objection> [!debate] The strongest objection> Disability-rights scholars argue that selecting against a trait expresses a judgement about people> Disability-rights scholars argue that selecting against a trait expresses a judgement about people> living with it. Savulescu's reply relies on a welfarist account of disability — a condition is a> living with it. Savulescu's reply relies on a welfarist account of disability, in which a> disability if it reduces expected wellbeing in the circumstances, not because it deviates from a> condition is a disability if it reduces expected wellbeing in the circumstances, not because it> norm — which critics say relocates the judgement rather than removing it. See> deviates from a norm. Critics say this relocates the judgement rather than removing it. See> [[disability-rights-and-enhancement]].> [[disability-rights-and-enhancement]]. ## Moral bioenhancement## Moral bioenhancement With Ingmar Persson, Savulescu argues that human moral psychology evolved for small groups withWith Ingmar Persson, Savulescu argues that human moral psychology evolved for small groups withlimited technology, and is poorly suited to a world where a few individuals can cause catastrophiclimited technology, and is poorly suited to a world where a few individuals can cause catastrophicharm.[^ps2008] Cognitive enhancement in this framing is dangerous on its own, because it increasesharm.[^ps2008] In this framing, cognitive enhancement on its own is dangerous, because it increasesthe capacity for harm without improving the disposition to avoid it. The proposed response isthe capacity for harm without improving the disposition to avoid it. The proposed response isresearch into biomedical means of strengthening altruism and a sense of justice — the illustrativeresearch into biomedical means of strengthening altruism and a sense of justice. The illustrativecandidates in the literature being oxytocin, serotonergic drugs and beta-blockers, none of whichcandidates in the literature are oxytocin, serotonergic drugs and beta-blockers, none of which doesdoes anything close to what the argument requires. Their 2012 book *Unfit for the Future* connectsanything close to what the argument requires. Their 2012 book *Unfit for the Future* connects thethe argument to [[existential-risk]].argument to [[existential-risk]]. The obvious objections have been pressed hard. John Harris argued that moral enhancement, ifThe obvious objections have been pressed hard. John Harris argued that moral enhancement, ifeffective, would remove the freedom to do wrong that makes moral action valuable.[^harris2011]effective, would remove the freedom to do wrong that makes moral action valuable.[^harris2011]Others ask who specifies the target morality, and note that any state with the capacity toOthers ask who specifies the target morality, and note that any state with the capacity toadminister moral enhancement is the last actor that should be trusted with it. Savulescu andadminister moral enhancement is the last actor that should be trusted with it. Savulescu and PerssonPersson's response distinguishes enhancing dispositions from determining choices, and accepts thatrespond by distinguishing the enhancement of dispositions from the determination of choices, andcompulsory application would be illegitimate. The empirical position is weaker than thethey accept that compulsory application would be illegitimate. The empirical position is weaker thanphilosophical one: no intervention has been shown to produce durable, general improvements in moralthe philosophical one: no intervention has been shown to produce durable, general improvements inbehaviour. See [[moral-enhancement]].moral behaviour. See [[moral-enhancement]]. ## Sport and doping## Sport and doping Savulescu has argued that the anti-doping regime is incoherent — it permits altitude tents,Savulescu has argued that the anti-doping regime is incoherent, because it permits altitude tents,hypoxic chambers and extensive pharmacological recovery while banning functionally similarhypoxic chambers and extensive pharmacological recovery while banning functionally similarinterventions — and that a safety-based regulatory model, monitoring physiological parametersinterventions. A safety-based regulatory model that monitors physiological parameters instead ofrather than prohibiting substances, would protect athletes better than prohibition does.[^sav2004]prohibiting substances would, he argues, protect athletes better than prohibition does.[^sav2004]The position is a minority one among sports physicians and anti-doping bodies, and it has becomeThe position is a minority one among sports physicians and anti-doping bodies, and it has becomemore salient with the emergence of openly enhanced competition formats. Seemore salient with the emergence of openly enhanced competition formats. See [[enhancement-in-sport]][[enhancement-in-sport]] and [[gene-doping]].and [[gene-doping]]. ## Reception## Reception The Uehiro Centre under Savulescu's direction trained a generation of researchers now working onThe Uehiro Centre under Savulescu's direction trained a generation of researchers now working onneuroethics, AI ethics and enhancement. His method is characteristicallyneuroethics, AI ethics and enhancement. His method is characteristically analytic. He states aanalytic: state a principle, follow it to conclusions most readers dislike, and treat the discomfortprinciple, follows it to conclusions most readers dislike, and treats the discomfort as data aboutas data about the principle rather than a reason to abandon it. Admirers regard this as intellectualthe principle rather than a reason to abandon it. Admirers regard this as intellectual seriousness.seriousness. Critics regard the same trait as a willingness to reach eugenic-sounding conclusionsCritics see in the same trait a willingness to reach eugenic-sounding conclusions through formallythrough formally valid steps, and note that his arguments almost always assume a regulatory andvalid steps, and note that his arguments almost always assume a regulatory and economic environmenteconomic environment in which access is fair — an assumption addressed at length inin which access is fair, an assumption addressed at length in [[access-and-inequality]].[[access-and-inequality]]. He is on the opposite side of most debates from [[leon-kass]], and the two positions define theHe is on the opposite side of most debates from [[leon-kass]], and the two positions define therange of serious argument in [[bioethics-of-enhancement]]: whether the given human form has moralrange of serious argument in [[bioethics-of-enhancement]]: whether the given human form has morallines 121–133 → 120–1321 unchanged line not shown
## Legacy## Legacy The practical test of Savulescu's programme is arriving now. [[embryo-selection]] on polygenicSavulescu's programme now faces a practical test. [[embryo-selection]] on polygenic scores isscores is commercially available and unregulated in several jurisdictions;commercially available and unregulated in several jurisdictions. [[in-vitro-gametogenesis]], if it[[in-vitro-gametogenesis]], if it works in humans, would remove the constraint that a cycle yieldsworks in humans, would remove the constraint that a cycle yields only a handful of embryos, and theonly a handful of embryos and would make the principle of procreative beneficence bind much harder.principle of procreative beneficence would then bind much harder. Savulescu has consistently heldSavulescu has been consistent that the resulting decisions belong to prospective parents rather thanthat the resulting decisions belong to prospective parents rather than states. Whether a technologystates. Whether a technology that makes his principle powerful also makes it acceptable is athat makes his principle powerful also makes it acceptable is a question his framework poses morequestion his framework poses more sharply than it answers.sharply than it answers. ## See also## See also removed, struck through added, underlinedLine numbers count the serialised markdown of each revision, frontmatter included.
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